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Madikwe & the Malaria-Free North — South Africa • Private Guided Travel
South Africa

Madikwe & the Malaria-Free North

South Africa • Region Guide

Discover Madikwe & the Malaria-Free North

For families with young children, travellers who prefer not to take antimalarial medication, and anyone seeking the Big Five without the Lowveld's mosquitoes, the malaria-free reserves of the North West Province are South Africa's quiet masterstroke. Madikwe Game Reserve—75,000 hectares of Kalahari-fringe bushveld on the Botswana border—is the jewel: one of the country's largest reserves, yet among its least crowded.

Madikwe is celebrated for the 'Super Seven'—the classic Big Five plus cheetah and the endangered African wild dog, which den here in numbers that make the reserve one of the continent's finest places to witness a pack on the hunt. Because there are no day visitors and lodge numbers are strictly capped, game drives feel genuinely private. Nearby Pilanesberg National Park, cradled in the crater of an extinct volcano, offers dramatic scenery and high wildlife density barely two hours from Johannesburg.

The accessibility is the gift: a short flight or scenic drive from OR Tambo delivers you into thick game country by lunchtime, with no prophylaxis required and lodges built to welcome children. It is the ideal safari for a first-time family, a multi-generational celebration, or anyone who wants their bush time uncomplicated.

What To See & Do

Highlights of Madikwe & the Malaria-Free North

  • Madikwe Game Reserve
  • African wild dog packs
  • Super Seven game viewing
  • Pilanesberg National Park
  • Malaria-free family lodges
  • Botswana border wilderness
What To Do

Luxury Safaris & Tours in South Africa

Curated private journeys designed for discerning travellers. Each safari is fully tailor-made and includes expert guides, luxury lodges, and unforgettable wildlife encounters.

Classic Kruger Safari

Classic Kruger Safari

Experience Africa's Premier Big Five Destination

📅 4 days / 3 nights4.9 (312)
Luxury Sabi Sands Safari

Luxury Sabi Sands Safari

Africa's Premier Leopard Territory — Unmatched Luxury

📅 5 days / 4 nights4.9 (247)
Cape Town & Safari Combo

Cape Town & Safari Combo

The Complete South Africa Experience — City, Wine & Wildlife

📅 10 days / 9 nights4.9 (189)
Ultimate South Africa Safari

Ultimate South Africa Safari

The Definitive 14-Day Journey Through South Africa's Greatest Treasures

📅 14 days / 13 nights5 (156)
Romantic Honeymoon Safari

Romantic Honeymoon Safari

Where Romance Meets the African Wild

📅 10 days / 9 nights5 (134)
Family Safari Adventure

Family Safari Adventure

100% Malaria-Free — Big Five Fun for All Ages

📅 8 days / 7 nights4.9 (167)
Photography Safari Expedition

Photography Safari Expedition

Master Wildlife Photography with Africa's Best Guides

📅 7 days / 6 nights4.9 (89)
Big Five Luxury Safari

Big Five Luxury Safari

Seven Days of Extraordinary Wildlife in Sabi Sands

📅 7 days / 6 nights4.9 (198)
Garden Route & Safari Experience

Garden Route & Safari Experience

Coast, Forest & Big Five — South Africa's Greatest Road Trip

📅 12 days / 11 nights4.8 (145)
Ultimate Big 5 SafariUltra-Luxury

Ultimate Big 5 Safari

Seven Days in Africa's Greatest Wildlife Sanctuary

📅 7 days / 6 nights5 (214)
Romantic Kruger Escape

Romantic Kruger Escape

A Five-Day Love Story Written in the Bushveld

📅 5 days / 4 nights4.9 (186)
Classic Safari Adventure

Classic Safari Adventure

Four Days of Big Five Magic at Genuine Luxury

📅 4 days / 3 nights4.9 (342)
Kruger Discovery

Kruger Discovery

Three Days, One Unforgettable First Safari

📅 3 days / 2 nights4.8 (408)
Leopard Capital UltimateUltra-Luxury

Leopard Capital Ultimate

Six Days in the Leopard Capital of the World

📅 6 days / 5 nights5 (198)
Intimate Big 5 Experience

Intimate Big 5 Experience

Five Days of Close Encounters in the Sabi Sand

📅 5 days / 4 nights4.9 (172)
Exclusive Bush Retreat

Exclusive Bush Retreat

Four Days of Luxury in the Heart of the Sabi Sand

📅 4 days / 3 nights4.8 (154)
Sabi Sands Explorer

Sabi Sands Explorer

Three Days in the World's Greatest Game Reserve

📅 3 days / 2 nights4.8 (143)
Ultimate Cape & Safari ComboUltra-Luxury

Ultimate Cape & Safari Combo

Seven Days of Mother City Glamour and Big Five Thrills

📅 7 days / 6 nights5 (207)
Cape Winelands & Coast

Cape Winelands & Coast

Five Days of Vineyards, Mountains and Atlantic Splendour

📅 5 days / 4 nights4.9 (178)
Table Mountain to Penguins

Table Mountain to Penguins

Four Days of Cape Town's Greatest Icons

📅 4 days / 3 nights4.8 (166)
Cape Town Highlights

Cape Town Highlights

Three Days in the Mother City

📅 3 days / 2 nights4.7 (151)
Ultimate Garden Route & Safari Combo

Ultimate Garden Route & Safari Combo

Eight Days of Coast, Forest & Big-Five Wilderness

📅 8 days / 7 nights4.9 (196)
Garden Route Coastal Adventure

Garden Route Coastal Adventure

Five Days of Forests, Beaches & Coastal Thrills

📅 5 days / 4 nights4.8 (224)
Garden Route Highlights

Garden Route Highlights

Four Days Along South Africa's Most Scenic Coast

📅 4 days / 3 nights4.8 (248)
Family Coastal Getaway

Family Coastal Getaway

Three Days of Family Fun on the Garden Route

📅 3 days / 2 nights4.8 (267)
Malaria-Free Big Five — Eastern Cape

Malaria-Free Big Five — Eastern Cape

The Big Five Without the Bite — Safe, Wild & World-Class

📅 5 days / 4 nights4.9 (274)
Eastern Cape Family Safari

Eastern Cape Family Safari

Big Five, Zero Malaria, Endless Smiles — Built for Families

📅 6 days / 5 nights4.9 (198)
Bush & Beach — Eastern Cape & Garden Route

Bush & Beach — Eastern Cape & Garden Route

Big Five, Ancient Forests & Wild Coast — The Perfect Pairing

📅 9 days / 8 nights5 (142)
Cape, Vines & Big Five Honeymoon

Cape, Vines & Big Five Honeymoon

Where Two Hearts Begin — Cape Town, the Winelands & a Private Big Five Reserve

📅 9 days / 8 nights5 (168)
Bush & Beach Honeymoon

Bush & Beach Honeymoon

Big Five Mornings, Indian Ocean Afternoons — Sabi Sand & the Islands of Mozambique

📅 10 days / 9 nights5 (142)
Ultimate Eastern Cape Big Five Safari

Ultimate Eastern Cape Big Five Safari

Malaria-Free Big Five Across Two Legendary Private Reserves

📅 6 days / 5 nights4.9 (168)
Amakhala Family Big Five Safari

Amakhala Family Big Five Safari

Malaria-Free Big Five for the Whole Family at Amakhala

📅 4 days / 3 nights4.8 (214)
Kariega Big Five & River Safari

Kariega Big Five & River Safari

Big Five Days, River Nights at Settlers Drift

📅 5 days / 4 nights4.9 (176)
Botlierskop Garden Route Safari

Botlierskop Garden Route Safari

Big Five on the Garden Route, Minutes from Mossel Bay

📅 3 days / 2 nights4.8 (143)
Malaria-Free Family Safari

Malaria-Free Family Safari

Big Five & Elephants for the Whole Family, No Tablets Needed

📅 5 days / 4 nights4.8 (231)
Addo Elephant & Garden Route Safari

Addo Elephant & Garden Route Safari

Big Five Bush and Garden Route Coast in One Journey

📅 7 days / 6 nights4.9 (154)
Luxury Sabi Sands Fly-In Safari

Luxury Sabi Sands Fly-In Safari

Johannesburg's Gateway to the World's Finest Leopard Territory

📅 4 days / 3 nights4.9 (268)
Johannesburg to Greater Kruger Luxury Safari

Johannesburg to Greater Kruger Luxury Safari

A Fly-In Big Five Escape from the City of Gold

📅 3 days / 2 nights4.8 (214)
Phinda Private Game Reserve Luxury Safari

Phinda Private Game Reserve Luxury Safari

Durban's Gateway to Malaria-Free Big Five Wilderness

📅 4 days / 3 nights4.9 (236)
Durban & Zululand Big Five Luxury Safari

Durban & Zululand Big Five Luxury Safari

KwaZulu-Natal's Legendary Rhino Country from the Warm Indian Ocean

📅 5 days / 4 nights4.8 (187)
Rovos Rail: Cape Town & Pretoria

Rovos Rail: Cape Town & Pretoria

The Pride of Africa — the world's most luxurious train, edge to edge across South Africa

📅 4 days / 3 nights4.9 (268)
The Blue Train: Cape Town & Pretoria

The Blue Train: Cape Town & Pretoria

A five-star hotel on wheels — South Africa's iconic blue journey with 24-hour butler service

📅 2 days / 1 nights4.8 (214)
Madikwe Malaria-Free Family Safari

Madikwe Malaria-Free Family Safari

Big Five in a Malaria-Free Wilderness — Made for Families

📅 4 days / 3 nights4.9 (176)
Madikwe Luxury Big Five Fly-In Safari

Madikwe Luxury Big Five Fly-In Safari

A Private, Malaria-Free Escape in South Africa's Finest Bushveld

📅 4 days / 3 nights4.9 (142)
Pilanesberg Big Five Safari

Pilanesberg Big Five Safari

Malaria-Free Big Five in an Ancient Volcanic Crater

📅 3 days / 2 nights4.8 (214)
Pilanesberg Luxury Safari & Sun City

Pilanesberg Luxury Safari & Sun City

Five-Star Bush Lodges Beside Africa's Legendary Resort

📅 4 days / 3 nights4.8 (158)
Hluhluwe-iMfolozi Rhino Safari

Hluhluwe-iMfolozi Rhino Safari

The Cradle of Rhino Conservation in Zululand

📅 3 days / 2 nights4.9 (168)
Zululand Phinda & Hluhluwe Luxury Safari

Zululand Phinda & Hluhluwe Luxury Safari

Seven Ecosystems, Both Rhino & the Wild Heart of KwaZulu-Natal

📅 5 days / 4 nights4.9 (142)
Painted Wolf Photographic Safari — Madikwe & Sabi Sand

Painted Wolf Photographic Safari — Madikwe & Sabi Sand

Two of South Africa's Great Wild-Dog Strongholds in One Journey

📅 7 days / 6 nights4.9 (118)
Sun City & Kruger Golf Safari

Sun City & Kruger Golf Safari

The Gary Player Country Club, the Lost City's Crocodiles, Then the Big Five

📅 7 days / 6 nights4.9 (96)
Leopard Creek & Sabi Sand Golf SafariUltra-Luxury

Leopard Creek & Sabi Sand Golf Safari

Golf on the Crocodile River Beside Kruger, Then the Leopards of the Sabi Sand

📅 7 days / 6 nights5 (74)
Fancourt Garden Route & Big Five Golf Safari

Fancourt Garden Route & Big Five Golf Safari

The Links at Fancourt, the Garden Route Coast, Then a Malaria-Free Big Five

📅 8 days / 7 nights4.9 (68)
Cape Winelands Golf & Safari

Cape Winelands Golf & Safari

Jack Nicklaus Golf Among the Vines, Cape Town, Then a Malaria-Free Big Five

📅 7 days / 6 nights4.9 (61)
Kruger Self-Drive Safari

Kruger Self-Drive Safari

The Tarred Loops, the Big Five and Rest Camps on the River — at Your Own Pace

📅 7 days / 6 nights4.9 (112)
Kgalagadi Self-Drive Safari

Kgalagadi Self-Drive Safari

Red Dunes, Riverbed Roads & the Famous Black-Maned Lions

📅 6 days / 5 nights4.9 (74)
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